German Commissioner Lohmann is planning his holidays when an unexpected phone call calls him back to work. A member of Interpol has been murdered. The head of an organization wants to come into contact with the gangster organization of Chicago. But who is this? Mysterious murders happen and all trails lead to a penitentiary. But there is Joe Como, FBI agent, who is helping commissioner Lohmann. But soon Lohmann doubts Comos’ identity. When Lohmann sees the name of Dr. Mabuse mentioned in a book found by a victim he believes that Dr. Mabuse is the mind behind the crimes. Starsring Gert Fröbe, Lex Barker, Daliah Lavi. Before the James Bond 007 movie Goldfinger, Gert Fröbe made two British-German movies featuring the diabolic mad scientist Doctor Mabuse and his nemesis, Commissioner Lohmann.